Fibrolamellar hepatocellular carcinoma (FHCC) is a rare form of hepatocellular carcinoma (HCC) that typically affects young adults and is characterized, under. Although fibrolamellar carcinoma (FLC) has conventionally been considered to be a histologic variant of hepatocellular carcinoma (HCC). Summary. An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible.

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National Center for Biotechnology InformationU. We report the case of a young woman with a large liver mass without evidence fibrolamelat chronic liver disease. Vilgrain V, Vullierme MP. On physical examination, he had no significant findings. First-choice treatment is surgical resection 1,5. Open in a separate window. Distribution permitted for non-commercial purposes only.

This behavior was compatible with HCC.

Recent results in cancer research Fortschritte der Krebsforschung. Only comments written in English can be processed.

Fibrolamellar hepatocellular carcinoma

Hepatology ; 49 catcinoma Cancer ; 46 2: Please review our privacy policy. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. This disease was first described by Edmondson in a year-old female with no underlying liver disease. Fibrolamellar carcinoma of the liver: Fibrolamellar hepatocellular carcinoma is a distinct histological variant of hepatocellular carcinoma characterised on microscopy by laminated fibrous layers between the tumor cells.


Metastatic Fibrolamellar Hepatocellular Carcinoma to the Pancreas

Log in Sign up. The AFP level was 3.

The lesion was mainly isoechogenic with hyperechogenic areas, located on left liver lobe and segment 4 Fig. Adenocarcinoma Familial adenomatous polyposis Hereditary nonpolyposis colorectal cancer.

Carcinoma hepatocelular sobre hígado no cirrótico

Focal nodular hyperplasia Focal nodular hyperplasia. J Fibrolamelaar Hematol Oncol. Abstract Fibrolamellar hepatocarcinoma is a rare neoplasm diagnosed by computed tomography and confirmed by anatomopathological examination.

Review of the clinicopathologic features of fibrolamellar carcinoma. Computed tomography of body with magnetic resonance imaging.

Summary An Orphanet summary for this disease is currently under development. It was irrigated by the left hepatic artery Fig. Fibrolamellar hepatocellular carcinoma Micrograph of fibrolamellar hepatocarcinoma showing the characteristic laminated fibrosis between the tumor cells with a low NC ratio.

Squamous cell carcinoma Adenocarcinoma. How to cite this article. The central scar typically shows persistent enhancement on delayed contrast enhanced CT. Hepatocellular adenoma Cavernous hemangioma hyperplasia: The surgical pathology from the resected specimens showed focal thin fibrous bands within the metastatic foci; however, definitive diagnostic features of a fibrolamellar variant of HCC were not identified within the metastatic lesions.


Fibrolamellar hepatocellular carcinoma: a case report

Cancer ; 6: Fibrolamellar variant of hepatocellular carcinoma. United European Gastroenterology Journal ;1 5: Laboratory tests were normal, except for a creatinine level of 1. Imaging of fibrolamellar hepatocellular carcinoma. Fibrolaelar, in this patient, metastasis occurred 30 years from first diagnosis and 26 years since his last resected liver recurrence. Lifelong surveillance should be considered in this type of hepatocelulsr, due to its propensity to recur many years after first presentation.

While sites of recurrence usually include the liver, regional lymph nodes, peritoneum, and lung [ 6 ], metastasis to the pancreas is extremely rare, with only 2 other cases reported in the literature to our knowledge [ 78 ]. Clinicopathologic characteristics and survival outcomes hepatpcelular patients with fibrolamellar carcinoma: In our study we found a solid, heterogeneous and encapsulated hepatic mass 13 x 10 cm.

Progres dans les recherches sur le cancer ;